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State Key Laboratory of Phytochemistry and Plant Resources in West China
CHEN Jijun's Group
CHENG Yongxian's Group
HAO Xiaojiang's Group
LIU Jikai's Group
LUO Xiaodong's Group
QIU Minghua's Group
ZENG Ying's Group
SUN Handong's Group
TAN Ninghua's Group
ZHANG Yingjun's Group
ZHAO Qinshi's Group
LUO Huairong's Group
LI Yan's Group
LI Shenghong's Group
YANG Yurong's Group
XIA Chengfeng's Group
ZHAO Jinhua's Group
QIN Hongbo's Group
WU Bin's Group
XU Gang's Group
ZHOU Jun's Group
LIU Haiyang's Group
XIONG Wenyong's Group
HU Kaifeng's Group
LI Fei's Group
Location: Home > State Key Laboratory of Phytochemistry and Plant Resources in West China > LI Yan's Group
 
LI Yan's Group
 
Professor LI Yan

  LI Yan, Professor of molecular pharmacology. The major research of our group is screening, research and development of new anticancer drugs from the natural compounds, investigating their action mechanisms andevaluating in vivo activity with xenograft mouse model. We are also focused our research and drug discovery on certain signaling pathways which are closely related with tumorigenesis,... More Content>>
Current Group Members
Group Leader:
  Prof. LI Yan (liyanb@mail.kib.ac.cn)
  Group Members:
  ZHOU Hongyu, PhD, associate professor, zhouhongyu@mail.kib.ac.cn
  LI Gentao, MSc, research assistant, ligentao@mail.kib.ac.cn
  YAN Juming, MSc, research assistant, yanjuming@mail.kib.ac.cn
  LIU Jianmei, MSc, research assistant, liujianmei@mail.kib.ac.cn
  KONG Lingmei, PhD student, konglingmei@mail.kib.ac.c... More Content>>
Major Research Achievements
We have set up a screening platform including cell-based assays, target-based assays and the animal model. With this assays, we detected the preliminary anti- tumor activity of more than 6000 drugs.
  We have screened inhibitors of tumorigenesis related signaling pathway from natural compounds, including WNT, NF-kappaB, mTOR pathways etc. A couple of potent molecules are obtained.
  We carr... More Content>>
News
Publicaions
1. Zhou HY, Shang CW, Wang M, Shen T, Kong LM, Yu CL, Ye ZN, Luo Y, Liu L, Li Y. 2016, Huang SL. Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK, Biochemical Pharmacology 116:39-50
  2. Wang M, Zhou AK, An T, Kong LM, Yu CL, Liu JM, Xia CF, Zhou HY, Li Y.2016, N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells, Jou... More Content>>
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