LI Yan, Professor of Molecular Pharmacology, Kunming Institute of Botany. Associate director of State Key Laboratory of Phytochemistry and Plant Resources in West China. Principle Investigator of Tumor Pharmacology and Chemical Biology. Education and Training: BSc: Shandong University, China PhD: Shandong University/German Cancer Research Center (DKFZ), 2001. Postdoctoral: ...
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Group Leader: Prof. LI Yan (liyan@mail.kib.ac.cn) Group Members: ZHOU Hongyu, PhD, Associate Professor, zhouhongyu@mail.kib.ac.cn KONG Lingmei, PhD, research associate, konglingmei@mail.kib.ac.cn AN Tao, PhD, research associate, antao@mail.kib.ac.cn GONG Yaxiao, MSc, research assistant, gongyaxiao@mail.kib.ac.cn ZHU Huifang, PhD student, zhuhuifang@mail.kib.ac.cn ...
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We have set up a screening platform including cell-based assays, target-based assays and the animal model. With these assays, we detected the preliminary anti- tumor activity of more than 10000 drugs. We have screened inhibitors of tumorigenesis related signaling pathway from natural compounds, including WNT, mTOR pathways etc. A couple of potent molecules were evaluated the activity t...
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1. Zhu H, Wang B, Kong L, An T, Li G, Zhou H, Gong L, Zhao Z, Gong Y, Sun H, Puno P*, Li Y*. Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin. Cell Chem Biol. 2019 Apr 16. pii: S2451-9456(19)30117-5. doi: 10.1016/j.chembiol.2019.04.003. 2. Zhou HY#, Yu CL#, Kong LM#, Xu XL, Yan JM, Li YC, An T, Gong L, Gong...
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