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State Key Laboratory of Phytochemistry and Plant Resources in West China
CHEN Jijun's Group
CHENG Yongxian's Group
HAO Xiaojiang's Group
LIU Jikai's Group
LUO Xiaodong's Group
QIU Minghua's Group
ZENG Ying's Group
SUN Handong's Group
TAN Ninghua's Group
ZHANG Yingjun's Group
ZHAO Qinshi's Group
LUO Huairong's Group
LI Yan's Group
LI Shenghong's Group
YANG Yurong's Group
XIA Chengfeng's Group
ZHAO Jinhua's Group
QIN Hongbo's Group
WU Bin's Group
XU Gang's Group
ZHOU Jun's Group
LIU Haiyang's Group
XIONG Wenyong's Group
HU Kaifeng's Group
LI Fei's Group
Location: Home > State Key Laboratory of Phytochemistry and Plant Resources in West China > LI Yan's Group > Major Research Achievements
Major Research Achievements

We have set up a screening platform including cell-based assays, target-based assays and the animal model. With this assays, we detected the preliminary anti- tumor activity of more than 6000 drugs.

We have screened inhibitors of tumorigenesis related signaling pathway from natural compounds, including WNT, NF-kappaB, mTOR pathways etc. A couple of potent molecules are obtained.

We carried out the mechanism study of the active compounds with molecular biology and labeled molecular probe. Together with the in vivo experiments, we evaluated the anticancer potential of certain compounds.

As a public technology platform, our labalso offers anticancer drug screening and preclinical pharmacological evaluation services to universities, research institutions and pharmaceutical companies.

 

 

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