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State Key Laboratory of Phytochemistry and Plant Resources in West China |
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Professor TAN Ninghua |
TAN Ninghua, Professor of phytochemistry. Major research interests include 1) chemistry and chemical biology of plant cyclopeptides: Discovery, structure, synthesis, biosynthesis, bioactivity, mechanism, evaluation for drug or probe; 2) chemistry, bioactivity and quality control of traditional Chinese medicines contained cyclopeptides; 3) e-Compound Library of Traditional Chinese Medicines...
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| Current Group Members |
Group Leader:
Prof. Dr. TAN Ninghua
Group Members:
Dr. ZHANG Yumei (Associate Professor, Phytochemistry)
Dr. ZENG Guangzhi (Research Assistant, Pharmacology)
Dr. YI Hua (Research Assistant, Organic Chemistry)
Dr. HE Wenjun (Research Assistant, Medicinal Chemistry)
Dr. XU Wenyan (Research Assistant, Medicinal Chemistry)
Mr. JI Changjiu (Technician, Medicinal ...
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| Major Research Achievements (since 2006) |
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Plant cyclopeptides: (1) Established the systematic chemical method for plant cyclopeptides including the new TLC detecting method, and discoverednearly 200 cyclopeptides from about 20 plants including 3 novel ones and about 100 new ones. (2) Tested several bioactivities, found about 30 active cyclopeptides and several hits, and clarified new mechanisms of one immunosuppressive and one antitumo...
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| Publications |
1. Grace G. L. Yue, Jun-Ting Fan, Julia K. M. Lee, Guang-Zhi Zeng, Tina W. F. Ho, Kwok-Pui Fung, Ping-Chung Leung, Ning-Hua Tan*, Clara B. S. Lau. Cyclopeptide RA-V inhibits angiogenesis by downregulating extracellular signal-regulated kinase 1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells. British Journal of Pharmacology, 2011, in press
2. Wen-Jun He, Zhao-Hui Fu, Guang-Zhi Z...
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