XIA Chengfeng, Professor of organic chemistry. Major research interests are total synthesis of complex natural products with interesting biological activities, which include the indole alkaloids melotenine A, alsmaphorazine, kopsihainanine, azonazine and others, as well as invariant natural killer T cell endogenous and exogenous antigens. E-mail: xiachengfeng@mail.kib.ac.cn
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Group Leader: Prof. Dr. XIA Chengfeng Group Members: Mr. LI Zhiyuan (Immunology) Mr. LI Dashan (Medicinal Chemistry) Ph. D. Candidates: Miss.NI Guanghui Mr. TONG Xiaogang Mr. DING Min Miss TU Dandan Mr. XIAO Zhichao
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Since this group was established in two years ago, we have synthesized 11 new NKT cells phospholipid antigens. By collaboration with De Libero group (Basel Hospital, Swiss), these antigens were proven to be the endogenous antigen for NKT maturation inside thymus. We also developed an efficient methodology to construct the pyrroloindole skeleton and are utilizing this method to synthesis of the ...
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