CHEN Jijun, Professor of phytochemistry. Major research interests are to involve in research and development of the naturally anti-virus including discovery of anti-HBV, anti-HIV and anti-depression active compounds, chemical modification, pre-clinical study of new drug from Traditional Chinese medicines. Email: chenjj@mail.kib.ac.cn
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Group Leader: Prof. Dr. CHEN Jijun Members: Dr. JIANG Zhiyong (Associate Professor) Dr. GENG Changan (Assistant Professor) Ms. ZHANG Xuemei (Senior engineer, technician) Mr. MA Yunbao (Senior engineer, technician) Mr. LUO Jie (Technician) Ms. HUANG Xiaoyan (Technician) Postdoctoral Fellows: Dr. LI Yaoli (2010-) Ph. D. Candidates: Miss WANG Ho...
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The protostane-type triterpenes from Alisma orentalis were revealed to have anti-HBV activity. Further chemical modification on the active compound alisol A provided 41 more active compounds from 154 synthezed derivatives. A significantly active compound with lower toxicity and good pharmacokinetic characteristic can act on the HBV C/preC and the X gene promoters, inhibit DHBV DNA load, and do ...
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