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State Key Laboratory of Phytochemistry and Plant Resources in West China
CHEN Jijun's Group
CHENG Yongxian's Group
HAO Xiaojiang's Group
LIU Jikai's Group
LUO Xiaodong's Group
QIU Minghua's Group
ZENG Ying's Group
SUN Handong's Group
TAN Ninghua's Group
ZHANG Yingjun's Group
ZHAO Qinshi's Group
LUO Huairong's Group
LI Yan's Group
LI Shenghong's Group
YANG Yurong's Group
XIA Chengfeng's Group
ZHAO Jinhua's Group
QIN Hongbo's Group
WU Bin's Group
XU Gang's Group
ZHOU Jun's Group
LIU Haiyang's Group
XIONG Wenyong's Group
HU Kaifeng's Group
LI Fei's Group
Location: Home > State Key Laboratory of Phytochemistry and Plant Resources in West China > ZENG Ying's Group > Major Research Achievements
Major Research Achievements
source:     author:     2016-04-28

  1. The biosynthetic origin of vibralactone in the basidiomycete fungus Boreostereum vibrans and evidence for its biosynthetic pathway which includes several very interesting reactions which may involve unusual enzymes (Angewandte Chemie International Edition 2013, 52, 2298-2302)




   2. A FAD-binding monooxygenase VibMO1 that converts prenyl 4-hydroxybenzoate into prenylhydroquinone and a divergent pathway to skeletally distinct meroterpenoids in B. vibrans from a common intermediate that has a shikimate-terpenoid origin, based on the traditional platform of precursor-directed biosynthesis and the analogous intermediates resulted (Angewandte Chemie International Edition 2016, 55: 5463–5466;http://onlinelibrary.wiley.com/doi/10.1002/anie.201510928/abstract) 






  3. Biosynthesis of pharmacologically active Isodon ent-kaurane diterpenoids

      Ent-kaurane diterpenoids, isolated from the Chinese medicinal herbs, Isodon L., are principle components showing potent bioactivities of antitumor and anti-autoimmune inflammation. We have cloned IeCPS1 and IeCPS2 encoding ent-copalyl diphosphate synthases (CPS) and verified that IeCPS1 and IeCPS2 are potentially involved in the biosynthesis of Isodon diterpenoids (Phytochemistry 2012, 76, 32-39).





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